Organic Anion Transporting
Na+-taurocholate co-transporting Polypeptides
ABTs (IBAT, ISBT)
Apical sodium-dependent Bile Acid Transporters
The knowledge of drug affinity and drug-drug interaction (DDI) to uptake and efflux transporters is a fundamental requirement in drug development, recommended by the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA).
Primacyt utilizes HEK-293 cells, each cell line is stable transfected with one uptake transporter protein. Our assays deliver information on the uptake, efflux and inhibitory potential of drugs and other compounds.